Plastic Surgery for Men QotD: GBL for "fat loss"?

GBL: Relaxation, calming, increased mental clarity, fat loss, use as a body or muscle "builder," recreational drug use, releasing growth hormone, improving athletic performance, trouble sleeping (insomnia), relieving depression and stress, prolonging life, improving sexual performance and pleasure, and other conditions.

 GBL Side Effects & Safety: Gamma butyrolactone (GBL) is UNSAFE. It is illegal to manufacture or sell GBL.

Use of GBL, or the closely related gamma hydroxybutyrate (GHB) and butanediol (BD), has been linked to deaths and cases of serious side effects. These serious side effects include bowel incontinence, vomiting, mental changes, sedation, agitation, combativeness, memory loss, serious breathing and heart problems, fainting, seizures, coma, and death. The effects can be made worse by alcohol or narcotics (opiates such as
morphine, heroin, and others). Long-term use may lead to withdrawal symptoms including insomnia, tremor, and anxiety.

GBL is UNSAFE and should not be taken by anyone. Certain people are at even more risk for side effects.

Do not take GBL if:

• You are pregnant or breast-feeding.
• You have epilepsy or a seizure disorder.
• You have high blood pressure.
• You have an irregular heartbeat.
• You are scheduled for surgery in the next two weeks. GBL might cause excessive sedation if combined with medications used during and after surgery.

Interactions:  

• Alcohol interacts with GAMMA BUTYROLACTONE (GBL)
  Alcohol can cause sleepiness and drowsiness. Taking GBL along with alcohol might greatly increase sleepiness and drowsiness caused by alcohol. Taking GBL along with alcohol can lead to serious side effects. Do not take GBL if you have been drinking.
• Amphetamines interacts with GAMMA BUTYROLACTONE (GBL)
  Amphetamines are drugs that can speed up your nervous system. GBL is changed in the body to GHB (gamma hydroxybutyrate). GHB can slow down your nervous system. Taking GBL along with amphetamines can lead to serious side effects.
• Haloperidol (Haldol) interacts with GAMMA BUTYROLACTONE (GBL)
  GBL can affect the brain. Haloperidol (Haldol) can also affect the brain. Taking haloperidol (Haldol) along with GBL might cause serious side effects.
• Medications for mental conditions (Antipsychotic drugs) interacts with GAMMA BUTYROLACTONE (GBL)
  GBL can affect the brain. Medications for mental conditions also affect the brain. Taking GBL along with medications for mental conditions might increase the effects and serious side effects of GBL. Do not take GBL if you are taking medications for a mental condition.
  Some of these medications include fluphenazine (Permitil, Prolixin), haloperidol (Haldol), chlorpromazine (Thorazine), prochlorperazine (Compazine), thioridazine (Mellaril), trifluoperazine (Stelazine), and others.
• Medications for pain (Narcotic drugs) interacts with GAMMA BUTYROLACTONE (GBL)
  Some medications for pain can cause sleepiness and drowsiness. GBL might also cause sleepiness and drowsiness. Taking GBL along with some medications for pain might cause severe side effects. Do not take GBL if you are taking medications for pain.
  Some medications for pain include meperidine (Demerol), hydrocodone, morphine, OxyContin, and many others.
• Medications used to prevent seizures (Anticonvulsants) interacts with GAMMA BUTYROLACTONE (GBL)
  Medications used to prevent seizures affect chemicals in the brain. GBL is changed in the body to one of these brain chemicals called GABA. Taking GBL along with medications used to prevent seizures might decrease the effects of GBL.
  Some medications used to prevent seizures include phenobarbital, primidone (Mysoline), valproic acid (Depakene), gabapentin (Neurontin), carbamazepine (Tegretol), phenytoin (Dilantin), and others.
• Muscle relaxants interacts with GAMMA BUTYROLACTONE (GBL)
  Muscle relaxants can cause drowsiness. GBL can also cause drowsiness. Taking GBL along with muscle relaxants might cause too much drowsiness and serious side effects. Do not take GBL if you are taking muscle relaxants.
  Some of these muscle relaxants include carisoprodol (Soma), pipecuronium (Arduan), orphenadrine (Banflex, Disipal), cyclobenzaprine, gallamine (Flaxedil), atracurium (Tracrium), pancuronium (Pavulon), succinylcholine (Anectine), and others.
• Naloxone (Narcan) interacts with GAMMA BUTYROLACTONE (GBL)
  GBL is changed by the body to another chemical. This chemical is called GHB. GHB can affect the brain. Taking naloxone (Narcan) along with GBL might decrease the effects of GBL on the brain.
• Ritonavir (Norvir) interacts with GAMMA BUTYROLACTONE (GBL)
  Ritonavir (Norvir) and saquinavir (Fortovase, Invirase) are commonly used together for HIV/AIDS. Taking both of these medications plus GBL might decrease how quickly the body gets rid of GBL. This could cause serious side effects.
• Saquinavir (Fortovase, Invirase) interacts with GAMMA BUTYROLACTONE (GBL)
  Saquinavir (Fortovase, Invirase) and ritonavir (Norvir) are commonly used together for HIV/AIDS. Taking both these medications plus GBL might decrease how fast the body gets rid of GBL. This could cause serious side effects.
• Sedative medications (Benzodiazepines) interacts with GAMMA BUTYROLACTONE (GBL)
  GBL might cause sleepiness and drowsiness. Medications that cause sleepiness and drowsiness are called sedatives. Taking GBL along with sedative medications might cause serious side effects. Do not take GBL if you are taking sedative medications.
  Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.
• Sedative medications (CNS depressants) interacts with GAMMA BUTYROLACTONE (GBL)
  GBL might cause sleepiness and drowsiness. Medications that cause sleepiness are called sedatives. Taking GBL along with sedative medications might cause serious side effects. Do not take GBL if you are taking sedative medications.
  Some sedative medications include clonazepam (Klonopin), lorazepam (Ativan), phenobarbital (Donnatal), zolpidem (Ambien), and others.
  
  The appropriate dose of gamma butyrolactone (GBL) depends on several factors such as the user's age, health, and several other conditions. At this time there is not enough scientific information to determine an appropriate range of doses for gamma butyrolactone (GBL). Keep in mind that natural products are not always necessarily safe and dosages can be important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

resource:  webmd.com

Pictured: The young woman ravaged by GBL - the legal party drug the Government won't ban

At 18, Mikaila Tyhurst was fit and healthy, with hopes of becoming an air stewardess.
At 22, her mind and body have been wrecked by addiction to a drug which is not even illegal yet.
Miss Tyhurst has been using the lethal party drug GBL - a cheap industrial chemical popular with clubbers - almost every day for four years.

The effects of GBL are etched on Mikaila Tyhurst's face. At 18, left, she dreamed of being an air hostess. Now at 22, she wants to regain control of her life

Her skin is blotchy and covered in spots, her eyes are puffy and her front teeth are missing after she fell and knocked them out.
She has severe liver damage, has been admitted to hospital - often unconscious - dozens of times and almost died of an overdose three months ago.
Yesterday Miss Tyhurst, from Crumpsall, Manchester, agreed to release these haunting pictures to serve as a warning to anyone thinking of dabbling with GBL.
'It has destroyed my life,' she said. 'I hope that by talking about what it has done to me it might stop someone else from trying it. When I look at the picture of myself at my 18th birthday party I feel sick at how much I have changed.'

Starting again: Mikaila is set to enter a detox programme to wean her off GBL. She has been admitted to A&E numerous times throughout her addiction

GBL - gamma butyrolactone - is a component of some paint strippers, nail varnish removers and superglue solvents.
Its use as a drug will become illegal by the end of the year after the Government agreed that it should be criminalised.

Thanks to her addiction Miss Tyhurst, a former shop assistant, no longer works. She is due to begin a detox programme this week. 'I am trying really hard to stop taking GBL but it is very hard, it is very addictive,' she said.

Hester Stewart, left, died after taking GBL. Mother Maryon Stewart has blasted the Government's plan to classify the drug as 'less dangerous than cannabis'

'I don't want to take it but when I stop I feel so sick. I am really excited about starting detox, I am going to make sure it works. I know this is my last chance.'

Dr Sean Cummings, who runs a private clinic for GBL users in Harley Street, said: 'This poor young girl looks ghastly, but unfortunately not dissimilar to some of my patients.

'GBL is extremely addictive and like heroin, it is very surreptitious - the addiction creeps up on you.

It may start out as a party drug, with users taking it on a Friday or Saturday night, then they may take an extra dose on a Sunday to help them sleep and before they realise they are taking it on a Monday, Tuesday and Wednesday as well.
'Some users take a dose every 40 minutes throughout the day to feel normal.'
 

The criminalisation of GBL follows a campaign by the mother of a medical student at Sussex University, who died after taking the drug during a night out in April.
Hester Stewart, 21, took only a small dose of GBL along with several alcoholic drinks before falling into a coma. Her mother Maryon, a renowned nutritionist, has welcomed the Government's decision to ban GBL, but is angry it is being made a Class C drug - the lowest classification. Other countries such as the U.S. which have banned GBL have placed it in their most serious class.
'GBL is every bit as dangerous as heroin and Ecstasy, if not more so, because it's lethal when combined with alcohol,' said Mrs Stewart, 55, from Brighton.
'Making it Class C sends out completely the wrong message. It should be a class A drug.'

Read more: http://www.dailymail.co.uk/news/article-1215733/Pictured-The-devastating-effects-legal-party-drug-GBL.html#ixzz0fYTrhil8